產(chǎn)品品牌：意大利UGO
產(chǎn)品型號(hào)：37140
爪腫測量儀設(shè)計(jì)用于風(fēng)濕關(guān)節(jié)炎、水腫、藥理作用等研究，精準(zhǔn)測量嚙齒類動(dòng)物肢體的腫脹情況。自上世紀(jì)60年代起，已經(jīng)有超過1000篇的引文。該儀器是大、小鼠炎癥水腫測量的理想工具，其測量分辨率是0.01ml。
整套儀器包含一個(gè)腳踏開關(guān)，用于記錄讀數(shù)，從而使得操作人員可以全神貫注于將動(dòng)物的爪侵沒于測量水杯中。液晶屏實(shí)時(shí)顯示實(shí)驗(yàn)數(shù)據(jù)，通過相應(yīng)軟件可方便的將實(shí)驗(yàn)數(shù)據(jù)導(dǎo)入電腦。
爪腫測量儀使用方法簡單，將腫脹的大鼠爪放入儀器的水槽中，導(dǎo)致水平面上升，爪腫測量儀測量出水平面上升引起的水壓力變化值，該壓力變化值對(duì)應(yīng)伸入水中腫脹大鼠爪的體積；對(duì)大鼠服用抗腫脹藥，大鼠的爪相應(yīng)消腫，將消腫的大鼠爪放入水槽中，導(dǎo)致水平面上升，爪腫測量儀測量出水平面上升引起的水壓力變化值，該壓力變化值對(duì)應(yīng)伸入水中消腫大鼠爪的體積，根據(jù)兩次水壓力變化值即體積的差值評(píng)估得出抗腫脹藥的效果。
特征
- 腳踏記錄實(shí)驗(yàn)數(shù)據(jù)
- 超過1000引文
- 多測量水杯可選
優(yōu)點(diǎn)：
- 免手持操作
- 絕大多數(shù)應(yīng)用開在參考文獻(xiàn)中查到
- 可用于大、小鼠實(shí)驗(yàn)
規(guī)格參數(shù)：
- 測量水杯直徑：1.3 cm (小鼠), 1.8; 2.5 & 3.5 cm (大鼠)
- 讀數(shù)分別率：0.01ml
- 與電腦連接：串行接口或USB接口
- 軟件：包含在標(biāo)配中
參考文獻(xiàn)：
et alia: “A2A Adenosine Receptors Are Differentially Modulated by Pharmacological Treatments in Rheumatoid Arthritis Patients and Their Stimulation Ameliorates Adjuvant-Induced Arthritis in Rats” PLoS ONE 8(1): e54195, 2013
§ T. Bertaim et alia: “Dose and Administration Schedule Effect of Tiludronate on Joint Damage in the Model of Complete Freund Adjuvant Induced Monoarthritis in Rats” Open Journal of Rheumatology and Autoimmune Diseases 3: 18-25, 2013
§ E. Borbély et alia: “Role of Tachykinin 1 and 4 Gene-Derived Neuropeptides and the Neurokinin 1Receptor in Adjuvant-Induced Chronic Arthritis of the Mouse” PLoS ONE 8(4): e61684,2013
§ R. Korhonen et alia: “Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1” Br. J. Pharmacol. 169 (7):1525-1536, 2013
§ A. Finlay et alia: “Sphingosine 1-Phosphate Mediates Hyperalgesia via a Neutrophil-Dependent Mechanism” PLoS ONE 8(1): e55255, 2013
§ D. Piomelli et alia:” Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism”. Nature NSC, 2010
§ L.H. Santos et alia: "Anti-Inflammatory, antinociceptive and Ulcerogenic Activity of a Zinc-Diclofenac Complex in Rats" Brazil. J. Med. Biol. Res. 37: 1205-1213, 2004
